Common use
Gestanin is a hormone progestogen similar to progesterone. The medication stimulates a secretory phase of the cyclic changes in endometrium and creates conditions for development of the fertilized egg, reduces contractile activity and sensitivity to oxytocin of the muscular outer layer of the uterus. Gestanin also activates growth of acini of the mammary glands, increases deposits of fat, promotes accumulation of liver glycogen and increases metabolism of glucose, increases production of aldosterone by the adrenal glands. Gestanin is used to prevent a miscarriage, a preterm birth.

Dosage and direction
Take exactly as prescribed by your doctor with a full glass of water or a meal to decrease stomach upset.

Precautions
Cautiousness should be exercised in patients with inflammatory kidney disease, chronic heart failure, reduced tolerance to glucose, and also in pregnant women. Monitoring of glucose blood levels is necessary in the patients with diabetes. Do not stop taking this medication suddenly without permission of your doctor as it may make your condition worse.

Contraindications
This medication cannot be used in patients with hypersensitivity to the medication, liver failure, Dubin-Johnson syndrome, Rotor syndrome, thrombophlebitis, cerebral blood circulation disorders, mammary gland and genital tumors, toxaemia (toxins in the bloodstream), herpes (also in history), and in breastfeeding women. Do not use this drug if you are under 16 years of age.

Side effects
The most frequent adverse reactions include allergic reaction, severe nausea and vomiting, dehydration, watery or bloody diarrhea, dyspepsia, headache, retention of fluid in the body, galactorrhoea (milky secretion from the breasts), breast tenderness, thrombophlebitis, thromboembolism, acne, weight gain, cholestatic jaundice, hyperthermia, insomnia or drowsiness, depression. If these symptoms become serious and bothersome contact your doctor.

Drug interaction
Inductors of microsomal oxidation reduce effects of Gestanin. Inform your doctor about all prescribed, over-the-counter drugs, herbal product and food supplements you use.

Missed dose
Take the missed dose as soon as you remember. If it is almost time of your next dose just skip the missed dose and return to your schedule. Do not double dose this medication to make up the missed dose.

Overdose
There is no information about overdose symptoms.

Storage
Store at room temperature between 20-25 C (68-77 F). Store away from moisture, heat, and sunlight. It is not recommended to store in a bathroom and places available for children.

Disclaimer
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.